产品货号:
Z24001
中文名称:
PPID抗体
英文名称:
Anti-PPID Antibody
产品规格:
50μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-PPID Antibody |
指标别名 | Cyclophilin 40;Cyclophilin D;Cyclophilin related protein;CYP 40;CYP40;CYPD;peptidylprolyl isomerase D;PPIase D;PPID;Rotamase D |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,FCM,IHC,IF |
基因名称 | PPID |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This Cyclophilin D antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 336-370 amino acids from the human region of human Cyclophilin D. |
计算分子量 | 41kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | PPIases accelerate the folding of proteins.It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.Proposed to act as a co-chaperone in HSP90 complexes such as in unligated steroid receptors heterocomplexes.Different co-chaperones seem to compete for association with HSP90 thus establishing distinct HSP90-co-chaperone-receptor complexes with the potential to exert tissue-specific receptor activity control.May have a preference for estrogen receptor complexes and is not found in glucocorticoid receptor complexes.May be involved in cytoplasmic dynein-dependent movement of the receptor from the cytoplasm to the nucleus.May regulate MYB by inhibiting its DNA- binding activity.Involved in regulation of AHR signaling by promoting the formation of the AHR:ARNT dimer;the function is independent of HSP90 but requires the chaperone activity.Involved in regulation of UV radiation-induced apoptosis.Promotes cell viability in anaplastic lymphoma kinase-positive anaplastic large- cell lymphoma (ALK+ ALCL) cell lines.May be involved in hepatitis C virus (HCV) replication and release. |
Uniprot ID | Q08752 |
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